24 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... syndromes Clinical ... ALT ↑ bilirubin level ... #Diagnosis #Management ... #Hematology #Rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - 80% have fever ... acid, Elevated Cr ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... common • Imaging: CXR ... Differentiation #Syndrome ... #management #hematology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... Radiology Imaging ... ON THE X-RAY! ... #diagnosis #msk ... #rheumatology
Supracondylar Elbow Fracture
• Most common elbow fracture in children, peak age 5-7 
• When looking at
), compartment syndrome ... • ED Management ... Elbow #Humerus #Radiology ... #XRay #Diagnosis ... #MSK
Monteggia Fracture 
Fracture of proximal ulnar shaft with radial head dislocation. Remember “MUGR” to recall where
), compartment syndrome ... Forearm #Ulnar #Radiology ... #XRay #Diagnosis ... #Management #Orthopedics ... #Proximal #MSK
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... following: • Fever ... lymph node, or liver ... #management #treatment ... #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... e.g. incidental CXR ... anterior/posterior MSK ... #Management #Signs
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Low serum IgG level ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Perilunate Dislocation
On lateral wrist XR, the capitate ("apple") should sit in the lunate ("tea cup") which
lateral wrist XR ... injury • ED Management ... Wrist #Carpal #Radiology ... #XRay #Diagnosis ... #Sports #MSK