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diagnosis hepatology rheumatology syndrome treatment blood hemophagocytic hlh lymphohistiocytosis oncology product reactions transfusion activation aflp air anemia antimda5 antimda5dm aplastic
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... 1999 - ICU FOCUS ... Blood saves lives ... unnecessary and cause ... Transfusion #Thresholds #Hematology
Kerion Raised, boggy lesion with heaped up purulent nodules Caused by host's response to a fungal ringworm
purulent nodules Caused ... mentagrophytes) Clinical ... Hair loss • Fever ... Griseofulvin #Kerion #Dermatology ... #Diagnosis #Management
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... Transfer to a liver ... #AFLP #Fatty #Liver
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
marine microbiota & causes ... Rapid onset of fever ... sepsis: chronic liver ... rash #cellulitis #dermatology ... #legs #clinical
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... disease and ILD • Liver ... Liver biopsies show ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
is the main clinical ... thrombocytopenia • Liver ... ALT ↑ bilirubin level ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
should encourage critical ... variety of other causes ... venousgas #ultrasound #hepatology ... #liver #pocus # ... clinical #air
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 Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... disease • Liver ... Low serum IgG level ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... following: • Fever ... lymph node, or liver ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
the setting of liver ... lung disease Caused ... shunt (Type 2) Clinical ... • Underlying liver ... hypertension • Liver
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