36 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Brain Failure Lung ... Failure Infections Alcohol-Associated ... #Cirrhosis #Hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Infection (EBV/CMV), Alcoholic ... 5-10x normal - Chronic ... AST:ALT > 2.5 - Alcoholic ... #Injury #hepatology ... transaminitis #differential
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... can be bridge to Liver ... #Hepatitis #Management ... #Algorithm #treatment ... #hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Sarcoidosis Toxic - Alcohol ... Nonalcoholic fatty liver ... heart failure (chronic ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... Diagnosis and Management ... Chronic Hepatitis ... Algorithm #Diagnosis #Management ... #Treatment #Hepatology
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Pharmacologic treatment ... Initiative for Chronic ... Obstructive Lung ... the perceived level ... #Management #Pulmonary
Alcoholic Hepatitis - Summary Overview
- Epidemiology
- Pathophysiology
- Clinical Features
- Labs
- Diagnosis
- Differential Diagnosis
- Treatment

Sarah Onorato @sonorato11

#Alcoholic
Alcoholic Hepatitis ... - Diagnosis - Differential ... Diagnosis - Treatment ... #Hepatitis #hepatology ... diagnosis #algorithm #management
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... e.g. ascites), Chronic ... hepatitis fibrosis ... Diagnosis #Algorithm #hepatology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue - Differential ... Renal Failure • Liver ... Epstein-Barr Virus • Hepatitis ... Obstructive Pulmonary ... Alcohol) • Drug
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... chemistry #diagnosis #differential ... #Hepatology #transaminitis