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diagnosis syndrome differential joint treatment activation antifungal approach calcium cppd deposition dermatology disease flutycosine gout hemophagocytic hlh lymphohistiocytosis macrophage mas
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
- Autoimmune Rheumatologic ... • Rheumatic fever ... streptococci (rheumatic fever ... #Diagnosis #MSK ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... is the main clinical ... juvenile idiopathic arthritis ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Flutycosine - Antibiotics Class Overview - Mechanism: 5-FC interferes with DNA and protein synthesis. Only
B for initial management ... - Virtually never ... infections) - Main ... adverse effects = Hematologic ... #Pharmacology #Antibiotics
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... acute rheumatic fever ... Lyme), reactive arthritis ... #Joint #Pain #MSK ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... rapidly, and empiric antibiotic ... agent are the main ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... thickening • Osteitis: pain ... syndrome with acne: antibiotics ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... Self-limiting, chronic but stable ... Extrapulmonary: ankle arthritis ... anterior/posterior MSK ... Sarcoidosis #Diagnosis #Management
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Diagnosis and Management ... swelling, significant pain ... frequent attacks • Arthritis ... Dual-energy CT → MSU ... #treatment #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
phenomenon (16%) MSK ... Arthralgia and Arthritis ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
onset of swelling, pain ... with acute neck pain ... , fever, and headache ... Deposition #Disease #Rheumatology ... #diagnosis #management
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