10 results
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... hemolytic anemia • Pain ... genes and gene products ... classification #hematology ... #oncology #management
Flutycosine - Antibiotics Class Overview
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Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
B for initial management ... - Virtually never ... infections) - Main ... adverse effects = Hematologic ... #Pharmacology #Antibiotics
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
is the main clinical ... ALT ↑ bilirubin level ... Fibrin degradation products ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... rapidly, and empiric antibiotic ... agent are the main ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Special Blood Product ... pain, dark urine ... Transfusions #diagnosis #management ... #hematology #reactions
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... activated macrophages produce ... Self-limiting, chronic but stable ... anterior/posterior MSK ... Sarcoidosis #Diagnosis #Management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine ... Blood products contain ... of transfused products ... Transfusion #diagnosis #management ... #hematology #reactions
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
phenomenon (16%) MSK ... Malignancy Risk: • Non-Hodgkins ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... swelling, significant pain ... Dual-energy CT → MSU ... Gout #diagnosis #management ... #treatment #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate produced ... onset of swelling, pain ... with acute neck pain ... Deposition #Disease #Rheumatology ... #diagnosis #management