13 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... Laboratory Tests ... Haptoglobin ↓ - Lactate
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... PD deficiency, Pulmonary ... Hemolytic uremic syndrome ... key #diagnosis #differential ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Myelodysplastic Syndromes ... Function Tests ... Function Tests ... Algorithm #Causes #Hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
presence of metabolic syndrome ... normalised ratio; LDH, lactate ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential #
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... Legionnaires disease • Pulmonary ... elevated serum LDH level ... • Tumor lysis syndrome
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
with leukopenia, anemia ... function tests ... ALT ↑ bilirubin level ... Triglycerides • ↑ Lactate ... Diagnosis #Management #Hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... or diagnostic tests ... output - Acute pulmonary ... - Compartment syndrome ... 30mmHg) - Severe anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... K), H. pylori test ... thyroid function test ... changes), high MCV anemia ... gastric bypass), LFT
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... • Diagnostic Test ... Donath-Landsteiner test
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Differentials? ... (short bowel syndrome ... Renal failure (uremia ... Anxiety, pain, fever ... Classically” noted with pulmonary