9 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Treatment: • Corticosteroids ... MAS #Macrophage #Activation ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... excessive macrophage activation ... Diagnosis: HLH signs ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... organ damage • Treatment ... TLS #diagnosis #management ... #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... Actively maintained fever ... hyperthermia crisis (late sign ... amphetamines) Toxic: • Radiologic ... Checklist #Diagnosis #Management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... sex • Metabolic syndrome ... double contour sign ... +Radiographic signs ... #treatment #rheumatology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... Signs of congestion ... acute coronary syndrome ... #differential #algorithm ... #management #cardiology
Alcohol Withdrawal Syndrome (AWS) - ICU OnePager

Scoring Alcohol Withdrawal Syndrome (AWS):
 • PAWSS
 • CIWA-Ar
 •
with normal vital signs ... instability (low grade fever ... diaphoresis) Treatment ... Ketamine by Nick ... #management #etoh
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... present with acute neck ... Deposition #Disease #Rheumatology ... #diagnosis #management
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Headache x1 mo, +neck ... organism (soap bubble sign ... CSF glucose level ... Standard treatment ... Brain #clinical #radiology