12 results
Validation of the Step-By-Step Approach to Febrile Infants

#Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
Infants #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... #Antibiotics #Risk ... Stratification #Fever
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... acute or subacute febrile ... following: • Fever ... #management #treatment ... #hematology
“Step by Step” – the new kid on the block – aims to risk stratify this
an infant with fever ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... Stratification #Fever
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
immunocompetent population Risk ... in lung>heart>liver ... symptoms, unexplained hematologic ... EBV viral load, signs ... #management #transplant
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Attempt if high risk ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... opacities • Diagnosis ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... Treatment: - If febrile ... Syndrome #TLS #diagnosis ... #management #hematology
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... 92.0% and 46.9% #Diagnosis ... #EBM #Management ... #Pediatrics #Peds ... Stratification #Fever
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Risk ... • Dyspnea • Fever ... lymph node biopsy (diagnostic ... classification #hematology ... #oncology #management
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
or family - Ever ... Intraabdominal - Orthopedic ... one post op Cardiology ... medical and surgical management ... stratification #diagnosis
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... inflammatory response Risk ... double contour sign ... +Radiographic signs ... #rheumatology