15 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... organ damage • Treatment ... TLS #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... hyperthermia crisis (late sign ... Phaeochromocytoma Neurologic ... #Hyperthermia #Differential ... Checklist #Diagnosis #Management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management ... #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Arthritis, AS Treatment ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Reversible course Differential ... elevated protein level ... #diagnosis #management ... #neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Muscle swelling - Fever ... #Diagnosis #Management ... #nephrology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
approach to the differential ... demyelination syndrome ... include vaptans (HF/liver ... #Hyponatremia #Differential ... #management #nephrology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Diagnosis and Management ... mild (malaise, fever ... Romana's sign ... Indeterminate form (No signs ... 90-120 days • Pediatric