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management febrile fever hematology infant lp oncology pediatrics risk stepbystep stratification anemia aplastic cardiology differential ebm emergencies encephalopathy endocarditis hemeonc
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... components of the algorithm ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds ... #LP #Antibiotics
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... • Bicytopenia Treatment ... rapidly, and empiric antibiotic ... #management #treatment ... #hematology
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
treatment. http ... 92.0% and 46.9% #Diagnosis ... Management #Pediatrics #Peds ... #LP #Antibiotics ... Stratification #Fever
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- β-lactam antibiotics ... index < 2 • EPO Level ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
elevated protein level ... persistent altered level ... epilepticus Treatment ... underlying cause • Treatment ... #neurology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
500 → may stop antibiotics ... interventional radiology ... → no immediate treatment ... after CRS) - Treatment ... Oncology #HemeOnc #Diagnosis
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
and Differential Diagnosis ... night sweats, fever ... Cholesterol emboli syndrome ... hematuria, + RF Treatment ... • IV antibiotics
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