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oncology algorithm disorders biliary causes cholangitis cirrhosis eosinophil eosinophilia erythematosus gap globulin hodgkins infectiousdiseases leukemia lupus management mds mycobacteria myelodysplasia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Metastatic cancer, Lymphoma ... Kawasaki, Nephrotic syndrome ... #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
during medical evaluation ... or workup for specific ... consider tissue biopsy ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Workup: • Full ... Immunohistochemical studies (to differentiate ... #diagnosis #classification ... #hematology #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... - Bone marrow evaluation ... BM aspiration/biopsy ... #Workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Lymphocytes - T or B lineage ... ALL is of B-cell lineage ... , weight loss, abdominal ... #Leukemia #Hematology ... #Oncology #Diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
higher • Liver biopsy ... bile ducts Differential ... Endocrinopathy, Lymphoma ... fungal, viral infections ... #workup #hepatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... with single-lineage ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
: • Syndrome of ... Hematologic malignancy ... enzymes, diarrhea, abdominal ... washings, Lung biopsy ... #differential #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... fibromyalgia) • Infections ... Malignancy (e.g. hematologic ... SLE • Kidney biopsy
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... changes (POEMS syndrome ... gastric tumors • Hematology ... #diagnosis #hematology
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