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differential management anemia aplastic chronic cll cryofibrinogenemia eczematous eosinophil eosinophilia essential et lymphocytic mds myelodysplasia myelodysplastic petechiae petechial physicalexam skinrash
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... • Screen for secondary ... symptoms (eg, skin ... #diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... in primary or secondary ... cryoglobulins • Skin ... #Algorithm #Causes ... #dermatology #physicalexam
Eczematous Skin Rash - Differential Diagnosis Algorithm Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated • Atopic Dermatitis
Eczematous Skin ... Diagnosis Algorithm ... Secondary to venous ... Eczematous #SkinRash #dermatology ... #Algorithm #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL is of B-cell lineage ... bone marrow and secondary ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... sudden onset of a rash ... - Rash: multiple ... Causes: - Idiopathic ... #dermatology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Hepatomegaly • Skin ... lymphoproliferative disorders ... #diagnosis #workup ... #oncology #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulinemia Associated Disorders ... arterial and/or venous ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... just beneath the skin ... DDX: Rule Out Secondary ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin ... and petechiae Causes ... virus (EBV) • Leukemia ... #hematology #diagnosis
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
megakaryocyte lineage ... • Treatment algorithms ... (if history of venous ... Thrombocythemia #ET #hematology ... #hematology
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