8 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Syndrome • Secondary ... disordersDiagnosis ... Syndrome #HES #Hematology ... eosinophils #diagnosis ... #management #algorithm
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... causes of eosinophilia ... symptoms (eg, skin ... #Disorders #Algorithm ... #hematology #eosinophilia
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Syndrome (HES) - Diagnosis ... and Management ... than 1500 and clinical ... Secondary Causes ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... bone marrow and secondary ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cryoglobulinemia Associated Disorders ... arterial and/or venous ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin ... and petechiae Causes ... #hematology #diagnosis ... #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... just beneath the skin ... DDX: Rule Out Secondary ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
megakaryocyte lineage ... (if history of venous ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology