13 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Systemic Lupus Erythematosus ... (Pancytopenia, WBC ... Non-Hodgkin's Lymphoma ... Algorithm #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
is of B-cell lineage ... - infiltrates (anemia ... -> Invade Skin: ... lymphoma #Leukemia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... • Neutropenia, anemia ... leukemia #CLL ... #diagnosis #workup ... #oncology #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Hyperthyroidism CBC ... • Lymphoma ... • Leukemia • Polycythemia ... Pruritus #primary #secondary ... #generalized #dermatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
5) Symptoms of anemia ... lymphoma (Richter ... marrow failure with anemia ... uw_IMresidency #CLL ... #oncology #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... • Lymphoma ... • Leukemia • Polycythemia ... #Pruritus #secondary ... #generalized #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... and leukemia • ... #Diagnosis #Rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
AIHA Primary Secondary ... - Monoclonal - Lymphoid ... Blood smear - RBC ... younger pts) Differential ... #hematology #diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full ... platelets - WBC ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
(HCV) • CLL & ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology