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disease activation adultonset behcet calcium cppd deposition infections infectiousdiseases lupus macrophage onset polychondritis pseudogout pyrophosphate relapsing signs sle symptoms
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Complications: MAS ... • Ocular: uveitis ... #management #treatment ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... Still disease ... [SLE], AOSD) • ... #Diagnosis #Management ... #Hematology #Rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... #disease #AOSD # ... diagnosis #rheumatology ... #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... Systemic disease ... Epidemiology: • Young adults ... #Syndrome #diagnosis ... #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, macular, patchy ... Differential Diagnosis ... rheumatoid arthritis, adult-onset ... Still disease, ... #Diagnosis #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Mycoses HISTOPLASMOSIS ... pulmonary symptoms • Rheumatologic ... Aspergillosis Pathophysiology ... osteoarticular, pulmonary, ocular ... #Diagnosis #Management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
chondritis • Ocular ... Sarcoidosis • Behcet ... ○ Syphilis ○ Fungal ... Polychondritis #rheumatology ... #diagnosis #management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Disease (CPPD) Pathophysiology ... a linear opacity ... Crowned Dens Syndrome ... Deposition #Disease #Rheumatology ... #diagnosis #management
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