22 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... = nonspecific (nausea ... Antithrombin Ill • Ultrasound ... iMedEducation #AFLP
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... in vitreous • Metastatic ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... synthesized in: liver ... Most cases diagnosed ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
significant portal HTN Signs ... obstruction) • Lack of signs ... sarcoidosis) • Liver ... metastasis • ... Fatty liver of pregnancy
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Tuberculosis: can cause ... • Lymphoma Metastatic ... vomiting • Fatigue Signs ... Symptoms: Reduced libido ... • Signs: Decreased
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... obstruction • ALP ... or higher • Liver
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... derangement of liver ... clinical symptoms/signs ... ALP, alkaline phosphatase ... mellitus; USS, ultrasound
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
-> Leg Ulcers, Livedo ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... circulation to veins -> Livedo ... Manifestations #pathophysiology ... #diagnosis #signs