9 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... cellular antigen, leading ... to complement activation ... Complement activation ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Type 1 - Mediators ... cell antigens, leading ... to complement activation ... #allergy #table
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
END-ORGAN DYSFUNCTION ... • Most common type ... Hemorrhagic → leading ... Classification #Types ... warm #wet #dry #table
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... IL-1 and IL-6, leading ... nervous system (CNS) dysfunction ... rash) • Heart, lung ... MAS #Macrophage #Activation
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
dissociation rate, leading ... agonist with a long ... mu-opioid-receptor activation ... the sublingual tablet ... Pharmacokinetics #Comparison #Table
Epinephrine - Anesthesia Pharmacology
Trade Name: Epinephrine
Brand Name(s): Adrenalin
Drug Type: Endogenous Catecholamine
Time of Onset: Rapid
Duration of Action:
Adrenalin Drug Type ... vasoconstriction - Activation ... contractility - Activation ... muscle in the lungs ... leading to dilation
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
event, follow ACC algorithm ... or LV dysfunction ... Risk Stratify Type ... What is the type ... unless prior heart/lung
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Kikuchi disease • Type-I ... pancreatitis, protein-losing ... mild cognitive dysfunction ... Chronic B-cell activation ... and leukemia • Lung
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
Langerhans cells, a type ... various tissues, leading ... • Endocrine Dysfunction ... Lungs: Cysts (esp ... marrow: Organ dysfunction