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Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Class I agents ... Channel Blockers⠀ Class ... agents in this class ... beta blockers.⠀ Class ... Channel Blockers Class
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Indications, Side Effects ... Eric Strong @DrEricStrong ... - Strong Medicine ... Channel #Blockers #ClassI ... #pharmacology #table
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
: CLASS 1 - Sodium ... channel blocking effects ... duration: - CLASS ... duration - CLASS ... 1C: Strong Blockade
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
: CLASS 1 - Sodium ... channel blocking effects ... duration - CLASS ... duration - CLASS ... 1C: Strong Blockade
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Hypokalemia - Differential ... Eric Strong https ... #Hypokalemia #Differential ... Low #Potassium #Table ... #Classification
Shock - Differential Diagnosis by Classification
Reflex Syncope 
 - Vasovagal syncope
   • Prolonged standing
Shock - Differential ... Diagnosis by Classification ... Medication side effect ... Eric Strong https ... #Table #Causes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Genetic defects ... Eric Strong https ... Hypomagnesemia #Differential ... Low #Magnesium #Table ... #Classification
Gerstmann Syndrome
1) Finger agnosia - Inability to name their own fingers, affecting both sides
2) Right-left confusion
- Inability to differentiate ... patient is still able ... to copy Causes ... : Stroke (main cause ... Injury, Tumor Localization
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Diagnosis Algorithm ... are present • Classic ... Lymphoproliferative #Disorders #Classification ... #algorithm
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
metabolic equivalent able ... ASA class If ... event, follow ACC algorithm ... Stable patients ... • <6mo since stroke