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Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Class I agents ... Channel Blockers⠀ Class ... agents in this class ... beta blockers.⠀ Class ... Channel Blockers Class
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Indications, Side Effects ... Eric Strong @DrEricStrong ... - Strong Medicine ... Channel #Blockers #ClassI ... #pharmacology #table
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
: CLASS 1 - Sodium ... channel blocking effects ... duration: - CLASS ... duration - CLASS ... 1C: Strong Blockade
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
: CLASS 1 - Sodium ... channel blocking effects ... duration - CLASS ... duration - CLASS ... 1C: Strong Blockade
Shock - Differential Diagnosis by Classification
Reflex Syncope 
 - Vasovagal syncope
   • Prolonged standing
Differential Diagnosis by Classification ... Medication side effect ... Medication side effect ... Eric Strong https ... #Table #Causes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Genetic defects ... Eric Strong https ... Low #Magnesium #Table ... #Classification ... #Causes #Workup
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology ... #differential #algorithm
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
metabolic equivalent able ... ASA class If ... event, follow ACC algorithm ... Stable patients ... • <6mo since stroke
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vasculitis) - Affects ... tract, and often causes ... Palpable purpura: strong ... differential #diagnosis #rheumatology ... #classification
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... mutations that affect ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology