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management diagnosis coccidioidomycosis comparison fungal latenttb pharmacology tb tuberculosis agents antifungals aspergillus betadglucan biomarkers causes differential galactomannan infections infectiousdiseases medications
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Lung abscess ... Lung Abscess - Clinical ... Blood cultures • CXR ... Cryptococcus - Coccidioides
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis. Fluconazole - Low
Overview of antifungal ... effects in the treatment ... hallucinations, rashes/long-term ... tolerable • Limited clinical ... Coccidioidomycosis #coccidioides
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Lymphoma • Lung ... Septic emboli • Lung ... abscess Primary ... • Progressive lung ... • Upper lobe lung
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Lymphoma • Lung ... Septic emboli • Lung ... abscess Primary ... • Progressive lung ... • Upper lobe lung
Antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis Fluconazole - Benefits: Low cost/tolerable
Antifungal agents ... effects in the treatment ... hallucinations, rashes/long-term ... Weaknesses: Limited clinical ... #coccidioides
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
dermatophytes, Coccidioides ... cut-offs defined in clinical ... admin of mold-active ... Clav (may be + as long ... setting of GVHD) ID
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
has five major clinical ... Sinusitis • Brain abscess ... change in the lungs ... • Serology for Coccidioides ... nails, bronchi, lungs
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