41 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... of Action Diuretics ... urearetics) 3) Loop ... Adenosine #Nephron #Pathophysiology ... #Action #nephrology
Ethacrynic acid - Conversion
Only loop diuretic without a sulfonamide substituent.
Rarely used alternative in patients who have
Ethacrynic acid - Conversion ... Only loop diuretic ... hypersensitivity reaction ... Ethacrynic #acid #Conversion ... #loop
Loop Diuretic Conversion - Dose Equivalents
Bumex (bumetanide) 1 mg PO
Demadex (torsemide) 20 mg PO
Lasix (furosemide) 40
Loop Diuretic Conversion ... to the site of action ... specific site of action ... have the dose conversion ... #Diuretic #Conversion
Mechanism of Action of Diuretics
Amiloride, Triamterene, Spironolactone
Loop Diuretics
Thiazides
Acetazolamide

#Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Mechanism of Action ... of Diuretics Amiloride ... Spironolactone Loop ... #Mechanism #Action ... #pharmacology #pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Hormones Acting ... Their Site of Action ... mannitol) 3) Loop ... Diuretics (e.g. ... spironolactone) #Pathophysiology
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop ... Diuretic Action ... Panel A, loop diuretics ... lumen by organic anion ... #Pathophysiology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... Remote use of loop ... blood pressure: Active ... Differential #Diagnosis #Algorithm ... #causes #urinary
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... , nasogastric suction ... anhydrase inhibitors, loop ... syndrome (mimics loop ... #Hypokalemia #Causes
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Metolazone Loop ... Pharmacology #nephrology #conversion ... #loop #thiazide ... #classes
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Ketoacidosis: Diabetic ... Ureterosigmoidostomy, jejunal loop ... , ileal loop ... Potassium-sparing diuretics