6 results
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Metabolic Alkalosis ... Remote use of loop ... or thiazide diuretics ... blood pressure: Active ... diuretic use, Bartter
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... Remote use of loop ... or thiazide diuretics ... blood pressure: Active ... #Metabolic #Alkalosis
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... vomiting/ nasogastric suction ... • Thiazide or loop ... diuretics after ... renal tubule diuretic
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
• Start with LOOP ... are short acting ... aldosterone states (CHF ... a contraction metabolic ... alkalosis & further
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
resistance • Metabolic ... alkalosis • Familial ... +2Cl- Symport (Loop ... the Nonspecific Cation ... Tolvaptan) • Treatment
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... alkalosis • Normal ... Surreptitious diuretic ... Rhabdomyolysis Treatment ... nephrology #management #pathophysiology