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nephrology diagnosis differential causes metabolic diuretics nephron pharmacology algorithm hypokalemia im loopdiuretic nejm resistance table urinary acidosis aniongap diuresis excretion
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop ... Diuretic Action ... Panel A, loop diuretics ... #Pathophysiology ... #Nephro #IM #LoopDiuretic
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
Algorithm - Urinary Chloride ... Remote use of loop ... or thiazide diuretics ... , Congenital chloride ... blood pressure: Active
Nephron Pathophysiology - Diuretic Sites of Action Diuretics 1) Acetazolamide/canagliflozin 2) Osmotic agents (mannitol, urearetics) 3) Loop agents (eg, furosemide) 4)
Nephron Pathophysiology ... of Action Diuretics ... urearetics) 3) Loop ... #Pathophysiology ... #Action #nephrology
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
a Mechanism of Diuretic ... high doses of loop ... diuretics are used ... thiazide-sensitive sodium chloride ... #Pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action 1) Acetazolamide 2) Osmotic
Hormones Acting ... on the Nephron - ... Site of Action ... mannitol) 3) Loop ... spironolactone) #Pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Metabolic Alkalosis ... Remote use of loop ... or thiazide diuretics ... blood pressure: Active ... diuretic use, Bartter
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
vomiting/ nasogastric suction ... • Thiazide or loop ... diuretics after ... renal tubule diuretic ... • Thiazide or loop
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... , nasogastric suction ... anhydrase inhibitors, loop ... syndrome (mimics loop
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Ureterosigmoidostomy, jejunal loop ... , ileal loop ... Generalized distal nephron ... Potassium-sparing diuretics ... loads (ammonium chloride
Major Segments of the Nephron and their Functions - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... acid and most diuretics ... limb of Henle's loop ... (TAL) - Active ... Segments #Function #Pathophysiology
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