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management nephrology diagnosis differential causes hyperkalemia chf heartfailure rhabdomyolysis acidosis algorithm aniongap cardiogenic checklist gitelman hfref high hormones im k
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... diuretics, and ... thiazide-like diuretics ... Postobstructive diuresis ... diuretic use),
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Diuretic Action ... Panel A, loop diuretics ... shown in Panel C, diuretics ... step can mediate diuretic ... #Pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action 1) Acetazolamide 2) Osmotic
the Nephron - Diuretics ... Acetazolamide 2) Osmotic Diuretics ... mannitol) 3) Loop ... Diuretics (e.g. ... Nephrology #Nephron #Diuretics
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... Fluids Shift potassium ... renal function) - Loop ... diuretic (often ... LouLectures #Hyperkalemia
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
G-K), K-sparing diuretics ... improve GFR - Diuresis ... hypertonic Amp IVP • Diuretics ... (IV loop diuretic ... diuretic (lasix
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
Non-reabsorbable anion ... High Urine Cl - Loop ... diuretics, Thiazide ... diuretics, Mg2+ ... #urine #potassium
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Ureterosigmoidostomy, jejunal loop ... , ileal loop ... Hypokalemia ... Potassium-sparing ... diuretics (amiloride
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment ... Monitor potassium ... Loop diuretics for ... Dialysis for severe hyperkalemia
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
with thiazide diuretic ... (renal potassium ... Surreptitious diuretic ... Rhabdomyolysis Treatment ... nephrology #management #pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
• LDH ↑ • Hyperkalemia ... oxidative injury Treatment ... Treatment of underlying ... Monitor potassium ... Loop diuretics for
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