6 results
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Remote use of loop ... or thiazide diuretics ... - Normal/low ... diuretic use, Bartter ... syndrome, Gitelman
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Remote use of loop ... or thiazide diuretics ... alkalosis • Normal/low ... diuretic use, Bartter ... syndrome, Gitelman
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
diuretics after ... renal tubule diuretic ... diuretics actively ... furosemide-like lesion) • Gitelman ... #Causes #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... alkalosis • Normal or low ... Surreptitious diuretic ... #Syndrome #diagnosis ... #pathophysiology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... tubular transport • Diuretics ... (loop/thiazide) ... Hypomagnesemia • Barrter's/Gitelman's ... MetabolicAlkalosis #NonGap #Nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... resistance • Metabolic ... +2Cl- Symport (Loop ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology