23 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Disease 3 Types ... originate from a low-grade ... Viral Infection Clinical ... fatigue, pallor, dyspnea ... #anemia #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... . primary cold agglutin ... , Copper and lead ... Extravascular #Causes ... differential #diagnosis #hematology
Wing-Beating Tremor of Wilson's Disease

Characterized by low frequency, high amplitude, near arm tremor caused by continuous
Tremor of Wilson's Disease ... Characterized by low ... near arm tremor caused ... #clinical #video ... #neurology #copper
Wing-Beating Tremor of Wilson's Disease

Characterized by low frequency, high amplitude, near arm tremor caused by continuous
Tremor of Wilson's Disease ... Characterized by low ... near arm tremor caused ... #clinical #video ... #neurology #copper
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Rarely dominate the clinical ... manifest on the face, upper ... Polyangiitis #GPA #dermatology
Wing-Beating Tremor on Physical Exam

Seen in Wilson's disease, caused by copper toxicity (low ceruloplasmin)

#Wing #Beating #Tremor
, caused by copper ... toxicity (low ceruloplasmin ... #PhysicalExam #clinical ... #video #neurology ... #copper
Erythema Annulare Centrifugum (EAC),
This is erythema annulare centrifugum (EAC), one of the “figurate erythemas.” These lesions
patient eats a lot ... Most cases are idiopathic ... drugs, systemic disease ... Centrifugum #EAC #clinical ... #photo #dermatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... in >90% - Low ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... • Cough • Dyspnea ... Increased Serum Copper ... number of sites of disease ... classification #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Prolonged PT/PTT • Low ... organ damage Clinical ... • Severe Liver Disease ... Treat primary cause ... treatment #management #hematology