15 results
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... Primary #Metabolic #Alkalosis ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... aldosteronism #Metabolic #Alkalosis ... Diagnosis #Algorithm #Nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic Alkalosis ... Chloridorrhea Renal ... • Penicillins Renal ... Hypomagnesemia • Barrter's/Gitelman's ... MetabolicAlkalosis #NonGap #Nephrology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Blood Work: - ... Hypomagnesemia - Metabolic Alkalosis ... dr_missyhanna #Gitelman ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... • Normal or low ... • Hypokalemia (renal ... Syndrome #diagnosis #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... mOsm/kg - Implies renal ... • Euvolemic (Low ... #Algorithm #nephrology ... #sodium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... ascending limb Gitelman ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Differential #Table
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
• Normal/low ... Bartter syndrome, Gitelman ... settings, the urine sodium ... the excretion of sodium ... urine #Algorithm #nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... Glucose, Acute resp. alkalosis ... FEPO4 ≥ 5% - Renal ... • Normal or Low ... #phosphate #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Decreased Intake: • Low ... - Metabolic alkalosis ... - Diarrhea • RENAL ... - Bartter - Gitelman ... Pathophysiology #Nephrology