6 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... Epithelial Cells Renal ... of epithelial sodium ... #Kidney #Nephrology ... #Differential #Table
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
alkalosis • Normal/low ... , Gitelman syndrome ... , Hypomagnesemia ... the excretion of sodium ... urine #Algorithm #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... alkalosis • Normal or low ... , Renal tubular ... #diagnosis #nephrology
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... after starvation, Acute ... steatorrhea) • Renal ... differential #diagnosis #nephrology ... #magnesium #low
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
postchronic hypercapnia (acute ... diuretics after renal ... generally indicates a renal ... tubule reabsorptive defect ... Diagnosis #Causes #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Sodium loss (diuretics ... can be high or low ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology