7 results
Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs)

What are the side effects?
 -
Check point inhibitors ... of check point inhibitors ... article- a great overview ... the checkpoint inhibitor ... #Oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
inducers (↑) and inhibitors ... concentrations, and inhibitors ... by inducers or inhibitors ... Pglycoprotein #inducers #inhibitors ... #Chemotherapy #Oncology
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Immune Checkpoint Inhibitor ... Toxicity Main ... CheckpointInhibitor #Toxicity ... Table #Diagnosis #Pharmacology ... #Oncology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Angiotensin-Converting Enzyme Inhibitors ... risk of digoxin toxicity ... increasing risk for toxicity ... Monoamine Oxidase Inhibitors ... supplementals #herbal #pharmacology
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity
Problem - Immune checkpoint inhibitors (ICIs) are associated with
Immune Checkpoint Inhibitor ... Immune checkpoint inhibitors ... Severity Grading ... #Checkpoint #Inhibitor ... Cardiotoxicity #cardiology #oncology
Chloramphenicol - Antibiotics Class Overview

– 50S ribosomal inhibitor.   IV or PO (but PO form
Antibiotics Class Overview ... 50S ribosomal inhibitor ... due to potential toxicity ... #Pharmacology #Antibiotics ... #Review #Overview
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
system (RAAS) inhibitor ... prophylactic RAAS inhibitor ... are limited HER2 Inhibitors ... prophylactic RAAS inhibitor ... #pharmacology #