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cardiology hematology management table cardiotoxicity chemotherapy interactions sideeffects adverse amiodarone anthracycline antibiotics checkpoint checkpointinhibitor chloramphenicol chronic cll cyp3a4 ddi doac
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
inducers (↑) and inhibitors ... concentrations, and inhibitors ... by inducers or inhibitors ... Pglycoprotein #inducers #inhibitors ... #Chemotherapy #Oncology
Immune Checkpoint Inhibitor Toxicity Main Toxicities: Colitis, Pneumonitis, Skin adverse events, Endocrine dysfunction, Hepatitis, Myocarditis,
Immune Checkpoint Inhibitor ... Toxicity Main ... SideEffects #Table #Diagnosis ... #Pharmacology # ... Oncology
Amiodarone Toxicity and Monitoring Tremor Ataxia Ocular neuritis Corneal Microdeposits Bradycardia Pulmonary fibrosis Hepatotoxicity Blue-gray skin
Amiodarone Toxicity ... Substrate CYP3A4 - Inhibitor ... #Amiodarone #Toxicity ... SideEffects #Adverse #Diagnosis ... #Management #Pharmacology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products Angiotensin-Converting Enzyme Inhibitors (ACEIs) • Night-blooming
Angiotensin-Converting Enzyme Inhibitors ... risk of digoxin toxicity ... increasing risk for toxicity ... Monoamine Oxidase Inhibitors ... supplementals #herbal #pharmacology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
CLL) - Summary Overview ... minimal tumor burden Diagnosis ... (Bruton kinase inhibitor ... Venetoclax (BCL2 inhibitor ... Lymphocytic #Leukemia #oncology
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity Problem - Immune checkpoint inhibitors (ICIs) are associated with
Immune Checkpoint Inhibitor ... Immune checkpoint inhibitors ... Severity Grading ... #Checkpoint #Inhibitor ... Cardiotoxicity #cardiology #oncology
Chloramphenicol - Antibiotics Class Overview – 50S ribosomal inhibitor. IV or PO (but PO form
Antibiotics Class Overview ... 50S ribosomal inhibitor ... due to potential toxicity ... #Pharmacology #Antibiotics ... #Review #Overview
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
work properly, leading ... methyltransferase inhibitors ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
system (RAAS) inhibitor ... prophylactic RAAS inhibitor ... are limited HER2 Inhibitors ... prophylactic RAAS inhibitor ... #pharmacology #
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