5 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
#DOAC #Bridging ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban ... #Loading #DVT #Pharmacology ... #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... @Bloodman #DOAC ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Dabigatran #Edoxaban
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... thereby leading to lower ... Dabigatran has moderate ... #Interactions #Table ... #Pharmacology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
the mainstay of VTE ... accelerates the bridging ... #Pharmacology #Pathophysiology ... Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... table ... of Therapy • Dabigatran ... Apixaban, Edoxaban, Rivaroxaban ... #pharmacology #