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hematology management oncology product reactions agglutinin alp anemia cbc classification coagulation cold dic differential disseminated eschar hemolytic hodgkins hyophosphatasia intravascular
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... Malnutrition • Wilson's disease ... deficiency • blood ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... presentation) • Cutaneous ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... #hematology #diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... of peripheral blood ... • Autoimmune diseases ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... organ damage Clinical ... • Severe Liver Disease ... #Coagulation #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... include: fever, cutaneous ... Malaria, Borrellia (Lyme ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... include: fever, cutaneous ... Malaria, Borrellia (Lyme ... #Transfusions #diagnosis ... #management #hematology
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... hyphae invading blood ... University Infectious Diseases ... #skin #clinical ... #photo
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... violaceous, nontender cutaneous ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Workup: • Full Blood ... marrow biopsy - if blood ... number of sites of disease ... classification #hematology
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