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management leukemia chronic cll algorithm common comparison cvid dermatologic diffuse gpa granulomatosis hemeonc hypogammaglobulinemia immunodeficiency immunology lad lymphadenopathy mds monoclonal
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
• Chronic Lymphocytic ... Leukemia (CBC with Lymphocytes ... - Monoclonal Lymphocytes ... #Causes #Hematology ... #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... cell neoplasm • Lymphocytes ... Absolute blood lymphocyte ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Hodgkin's Lymphoma ... Hodgkin's Lymphoma ... , Hodgkin Lymphomas ... #diagnosis #differential ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of cases) Classification ... HL (MCHL) - Lymphocyte ... HL (LRHL) - Lymphocyte ... LDHL) - Nodular lymphocyte ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... morphologically mature B Lymphocytes ... rnature-appearing lymphocytes ... 500/uL clonal B lymphocytes ... #hematology #hemeonc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... CLL (Chronic Lymphocytic ... Leukemia): • Lymphocytes ... #Leukemia #Hematology ... #Oncology #Diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... disease • Non-Hodgkin ... Polyangiitis #GPA #dermatology ... #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... salivary ducts Clinical ... UIP, NSIP): • Lymphocytic ... Malignancy Risk: • Non-Hodgkins ... Sjogrens #Syndrome #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Granulomatous lymphocytic ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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