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oncology leukemia rheumatology syndrome blood chronic lymphocytic product reactions antimda5dm antinxp2 antinxp2dm classification clinical common cvid dress hemeonc hodgkins hypogammaglobulinemia
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... severity of the disease ... #AntiMDA5 #Dermatomyositis ... dermatology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Diagnosis: • ... cells can indicate disease ... microglobulin Treatment ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
rash in association ... Atypical Lymphocytes ... : symptomatic treatment ... DRESS #Syndrome #dermatology ... #diagnosis #management
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
contagious of all ... Skin rash and malaise ... resembling rashes caused ... #Diagnosis #Clinical ... #Photo #Dermatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Causes: - Idiopathic ... , breast CA - Hematologic ... Treatment: - Systemic ... #dermatology #oncology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Muscle atrophy may cause ... had more severe disease ... positive patients Treatment ... #diagnosis #management ... dermatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Granulomatous lymphocytic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... UIP, NSIP): • Lymphocytic ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Diagnosis #Management
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