8 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... dosing and bridging ... #Bridging #Dosing ... #Oral #Anticoagulant ... #Hematology
Oral Anticoagulation - VTE and DVT Bridging

- Amelia Furbish PharmD Student @ https://www.instagram.com/happypillsrx/

#DOAC #Oral #Anticoagulant #VTE
Oral Anticoagulation ... - VTE and DVT Bridging ... happypillsrx/ #DOAC ... #Oral #Anticoagulant ... #Dosing #Pharmacology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... for appropriate dosing ... #Anticoagulation ... #Management #Hematology ... #Oncology
Anticoagulant Bridging

 • Switching from LMWH
 • Switching from UFH
 • Switching from DOAC to Warfarin
Anticoagulant Bridging ... Kfischer_10 #Anticoagulant ... #Bridging #anticoagulation ... #pharmacology # ... management #hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
bleeding risk during ... DOAC, direct oral ... #Anticoagulation ... #Management #Hematology ... #Oncology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
procedure Stop anticoagulant ... treatment; volume ... #Oral #anticoagulant ... #hematology #management ... #pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... direct acting oral ... anticoagulants ... clearance (calculated using ... #pharmacology #
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology