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oncology chronic classification cll differential hlh hodgkins hypogammaglobulinemia icl idiopathic immunodeficiency immunology leukemia lymphocytopenia lymphohistiocytosis lymphoma lymphopenia sjogrens summary treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... cell neoplasm • Lymphocytes ... surface molecules: CD5 ... #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
Idiopathic CD4 Lymphopenia ... • Persistent CD4 ... mL or 20% total lymphocyte ... #hematology #Differential ... #Causes #lymphocytopenia
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Granulomatous lymphocytic ... DDX - Other causes ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
(HLH) Pathophysiology ... →Activation of CD8 ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... /aggregate) of CD4 ... UIP, NSIP): • Lymphocytic ... #Rheumatology # ... Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
HL (MCHL) - Lymphocyte ... HL (LRHL) - Lymphocyte ... LDHL) - Nodular lymphocyte ... Hodgkin Lymphoma Workup ... classification #hematology
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