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diagnosis differential hepatology causes primary dermatology lfts pbc pruritus secondary systemic abnormal ascites cholangitis enzymes hepatitis hepatomegaly injury liverenzymes management
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Diagnose PBC if 2/3 criteria ... Liver biopsy findings ... #Algorithm #hepatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Differential Diagnosis Algorithm ... • Cholestatic liver ... disease Creatinine ... Myelodisplastic syndrome Psychiatric
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Pathophysiology: • T lymphocyte ... /Liver failure ... or higher • Liver ... diagnosis #workup #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... Cholangitis • Primary Biliary ... Cirrhosis #Hepatomegaly ... #Causes #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Cholestatic disease ... Infiltrative • Cirrhosis ... Duct Stone • Biliary
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
- Hepatic: • Cirrhosis ... • Infiltrative disease ... • Acute liver ... failure • Primary biliary ... #Hepatology #causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Extrahepatic - Biliary ... hepatitis: < 1 • Cirrhosis ... differential #diagnosis #algorithm ... #hepatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
• Cholestatic liver ... disease Creatinine ... Myelodisplastic syndrome Psychiatric ... secondary #systemic #generalized ... #dermatology #Differential
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... metabolic syndrome criteria ... include extrahepatic biliary ... disease; T2DM, ... #Hepatology #Liver
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... vasculitis: 10%-16% Liver ... hepatitis, primary biliary ... cirrhosis: 3%-20% ... Nephrogenic DI Hematologic
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