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diagnosis hematology differential oncology causes dermatology generalized leukemia pruritus systemic abnormal cll common cvid enzymes hypogammaglobulinemia immunodeficiency immunology lfts liver
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... cells can indicate disease ... • Richter’s Syndrome ... #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... • Tumor lysis syndrome ... bone marrow and secondary ... #Leukemia #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... Psychiatric Disease ... Pruritus #primary #secondary
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... for workup, including ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... Autoimmunity • Chronic ... Granulomatous lymphocytic ... : • Nephrotic syndrome ... Malignancies • Chronic
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... urgent referral to secondary ... presence of metabolic syndrome ... criteria should ... #Hepatology #Liver
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... normal/high - Chronic ... can drive this disease ... As with many disease ... #workup #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Cholestatic liver disease ... Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... Psychiatric Disease ... #Pruritus #secondary
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... Myeloproliferative Disease ... Workup: • Complete
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