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hematology management differential disease oncology pediatrics activation causes cd4 classification ddxof hodgkins icl idiopathic incomplete leukemia lymphocytopenia lymphopenia macrophage polychondritis
Algorithm for the Evaluation of Kawasaki and Incomplete Kawasaki Disease: Diagnosis * Fever >5d * Criteria (4/5) -
Algorithm for the ... Disease: Diagnosis ... * Fever >5d * ... ) #Diagnosis #Peds ... #Workup #Algorithm
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... lymph node biopsy (diagnostic ... through Ann Arbor criteria ... #diagnosis #classification ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL: mediastinal mass ... Headaches, bone pain, fever ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology ... #Oncology #Diagnosis
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
suspected incomplete Kawasaki ... old on day ≥7 of fever ... within 10 d of fever ... #Diagnosis #Peds ... #Pediatrics #Kawasaki
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Activation Syndrome (MAS ... erythematosus • Kawasaki ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
CRITERIA FOR ICL ... mL or 20% total lymphocyte ... Unc119) • Heme (lymphoma ... MTB/MAC • Common ... #hematology #Differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis: • Fevers ... • Check: HBV Kawasaki ... elevated protein, lymphocytic ... #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Nonspecific symptoms: Fever ... and fatigue Criteria ... Viral infection • Lymphoma ... Polychondritis #rheumatology ... #diagnosis #management
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