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causes differential algorithm hemolysis hemolytic management nephrology acute aki crisis dermatology disorders extravascular injury intravascular kidney mds myelodysplasia myelodysplastic neurology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Increased Serum bilirubin ... Hemolysis #Hemolytic #Anemia ... #Workup #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... result in severe anemia ... Indirect bilirubin ... impairment #TTP ... #Workup #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... Refractory ITP, ... #Causes #Workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... thrombocytopenic purpura (TTP ... usually IgG) (e.g. lupus ... #hematology #anemia
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... and Differential Diagnosis ... intravesicular pressure • TTP ... , haptoglobin, bilirubin ... #nephrology #causes
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Differential Diagnosis ... fulminans - DIC - TTP ... Autoimmune Vasculitis (lupus ... deficiency Work
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Thrombocytopenia (ITP ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Syndrome (SPS) - Diagnosis ... Prevalence: 1-2 cases ... and pernicious anemia ... antibody that works ... autoantibodies - TPO, TTG
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
microangiopathic hemolytic anemia ... • Refractory cases ... PLEX (overlap TTP ... Renal #Crisis #rheumatology ... #nephrology #diagnosis
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