9 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... initiation • Differential ... : Diuresis for fluid ... APML #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
axonal form • MRI ... Treatment: • Plasmapheresis ... ventilation • Steroids ... #diagnosis #management ... #treatment #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... weakness, arms > legs ... life-threatening Differential ... Immunosuppressive Therapies: Steroids ... Gravis #diagnosis #management
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
(LEMS), systemic ... clinical index (SAMS-CI ... statin • Oral steroid ... myopathy #diagnosis #management ... #treatment
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... needing a little fluid ... acute coronary syndrome ... #diagnosis #differential ... #algorithm #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Differential Diagnosis ... Beckwith Wiedemann syndrome ... IGF-1 level (↑Sens ... • Pituitary MRI ... Endocrinology #Treatment
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... Cerebrospinal fluid ... oligoclonal bands • MRI ... purpura (lower legs
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
flexors of the legs ... Transverse Myelitis Treatment ... : • Steroids ... Myelitis #diagnosis #management ... #neurology #differential
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
locations: Wrist, MCP ... Hypomagnesemia Synovial Fluid ... Acute Pseudogout: Treatment ... Syndrome: • A ... Rheumatology #diagnosis #management