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rheumatology hematology dermatomyositis hemophagocytic hlh lymphohistiocytosis syndrome antimda5 antimda5dm antinxp2 antinxp2dm behcet brain cns crypto cryptococcal differential disease encephalitis hemeonc
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
- Differential Diagnosis ... Maculopapular rash ... • Common clinical ... Acute meningeal signs ... • Uveitis • Rash
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... The signs and symptoms ... ▪ “Rash” (75% ... #Diagnosis #Clinical ... #Photo #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... : HLH signs and ... #management #treatment ... #hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... auricular papules Clinical ... #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Petechial or purpuric rash ... 5000 to 10,000 ng/mL ... #Syndrome #Diagnosis ... #Management #Hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... lesions, aseptic meningitis ... Behcet syndrome (Clinical ... ) Differential Diagnosis ... #management #signs
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... auricular papules Clinical ... #management #rheumatology ... #dermatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... HLH is a critical ... Clinical Presentation ... • Common Signs ... #Management #Hematology
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Diagnosis? ... organism (soap bubble sign ... drained at time of diagnosis ... is typically 20 ml ... T2 #MRI #Brain #clinical
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