10 results
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Secondary Causes ... Malignancy - Immunologic ... #diagnosis #hematology ... #differential # ... management #eosinophils
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Syndrome • Secondary ... underlying hematologic disorders ... Syndrome #HES #Hematology ... #eosinophilia # ... #management #algorithm
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Screen for secondary ... #Disorders #Algorithm ... #Differential # ... diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... Diagnosis Secondary ... Chronic inflammatory disorders ... myeloid leukemia (CML ... #secondary
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
vasculitis) or disorders ... of primary or secondary ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential ... #Ddxof
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... and M panel Management ... hypogammaglobulinemia #immunology ... #management
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... pass = Dangerous secondary ... ESRD & CAD • Eosinophilic ... GI Disorders ... #Diagnosis #hematology
Pathergy Summary Overview

What is pathergy?
Pathergy is an exaggerated skin injury occurring after minor trauma such as
interferon-alpha • Atypical eosinophilic ... Myeloproliferative disorders ... Pathergy #diagnosis #differential ... #allergy #immunology ... #dermatology #skin
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... classical HL (MCHL ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... DDX: Rule Out Secondary ... Myelogenous Leukemia (CML ... Neutropenia • Platelet Disorders ... blood count with differential