33 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bleeding disorder Clinical ... bruising • Skin ... VonWillebrand #Disease #Diagnosis ... #Hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Differential Diagnosis ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Scleroderma Associated Telangiectasia. 

If you see them-round, often well circumscribed (but can be matte-like too) &
Telangiectasia #clinical ... #video #blanching ... #skin #dermatology ... #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
predispose to other orthopedic ... common sites: hip, shoulder ... #differential #diagnosis ... #causes #hematology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's sign is a clinical ... differentiating between the diagnosis ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam #Video ... #Clinical #SJS
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
, and back and shoulders ... dorsal part of the MCP ... auricular papules Clinical ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Clinical ... Cryofibrinogenemia Diagnosis ... : • + Clinical ... #rheumatology # ... hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Ferritin >500 ng/mL ... • Infection should ... antibiotic therapy should ... management #treatment #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... Differential Diagnosis ... Lymphomas • Other hematologic ... Malignancies (eg CML ... #differential #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... diagnosis • Rule ... SAPHO #Syndrome #Rheumatology ... #Dermatology