8 results
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
- Pathophysiology ... New-onset fever with rash ... #Diagnosis #Dermatology ... #Rash #Maculopapular ... #Differential #Ddxof
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... #Diagnosis #Dermatology ... #Rash #Erythroderma ... #Differential #Ddxof
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... dorsal part of the MCP ... #rheumatology # ... dermatology #diagnosis
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Pathophysiology: ... #Diagnosis #Dermatology ... #Rash #Petechiae ... #Differential #Ddxof
Gottron's Papules in Dermatomyositis

Another classic clue is Gottron's papules which are small grouped flat topped papules
Gottron's Papules in Dermatomyositis ... surfaces of joints (MCP ... Gottrons #Papules #Rash ... #Dermatomyositis ... #Dermatology #Clinical
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Still disease, dermatomyositis ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... La, anti-Jo-1, SCL
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... with leukopenia, anemia ... 5000 to 10,000 ng/mL ... Diagnosis #Management #Hematology ... #Rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... dorsal part of the MCP ... diagnosis #management #rheumatology ... #dermatology