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diagnosis rheumatology antinxp2 antinxp2dm crisis dermatology erythematosus hemeonc hemophagocytic hlh lupus lymphohistiocytosis macrophage nephrology renal scleroderma sle src syndrome systemic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Petechial or purpuric rash ... with leukopenia, anemia ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Still disease, dermatomyositis ... Malignancy (e.g. hematologic ... lymphopenia, low PLT • Anemia ... La, anti-Jo-1, SCL ... Chronic B-cell activation
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... dorsal part of the MCP ... #diagnosis #management ... dermatology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
microangiopathic hemolytic anemia ... (MAHA) Pathophysiology ... is unknown but may ... endothelial cell activation ... of arteries Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... (often termed MAS-HLH ... - Cytopenias (anemia ... Pathophysiology ... #Hematology #HemeOnc
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