21 results
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
ULN R - Renal disease ... Causes of false- ... amyloidosis Other causes ... MGUS #diagnosis #hematology ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... IFN-y) → Excessive activation ... accumulation of clinical ... Assessment • Clinical
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
chronic liver disease ... University Infectious Diseases ... #cellulitis #dermatology ... #legs #clinical ... #photo
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Fever is the main clinical ... Petechial or purpuric rash ... 5000 to 10,000 ng/mL ... Diagnosis #Management #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
• Clinical features ... Lymphomas • Other hematologic ... Malignancies (eg CML ... NonHodgkins #comparison #oncology ... #differential #hematology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
stages of this disease ... resembling rashes caused ... by other diseases ... #Diagnosis #Clinical ... #Photo #Dermatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... sequestration and activation ... without other cause ... Transfusion #Reactions #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Malignancy (e.g. hematologic ... lymphoproliferative syndrome Clinical ... La, anti-Jo-1, SCL ... Chronic B-cell activation
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... age, however the disease ... Ferritin >500 ng/mL ... management #treatment #hematology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... gram-negative bacillus cause ... University Infectious Diseases ... #dermatology #clinical ... #photo