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rheumatology management erythematosus lupus systemic treatment cutaneous dermatology hemeonc hemophagocytic heparin hit hlh induced lymphohistiocytosis macrophage mas mucormycosis photo signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... ) Blood (75%): Anemia ... signs #symptoms #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Petechial or purpuric rash ... erythematosus [SLE ... with leukopenia, anemia ... #Syndrome #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... Autoimmune diseases: SLE
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
arterial thrombosis, skin ... ♀, ↑Age, ESRD Pathophysiology ... complex → plt activation ... Confirmatory test ↑Se ... Management #Treatment #Hematology
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... malnutrition, HIV, SLE ... trauma, aplastic anemia ... #dermatology #skin ... #clinical #photo
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