9 results
Bulge Sign to demonstrate a Knee Effusion on Physical Examination

Dr. Janet Pope @Janetbirdope

#Bulge #Sign #Knee #Effusion
a Knee Effusion ... #Knee #Effusion ... #PhysicalExam #clinical ... #video #msk #sports ... #orthopedics #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... erythematosus [SLE ... 5000 to 10,000 ng/mL ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
The Bulge Sign in Knee Effusion

Highly specific sign for knee joint effusion. 
 - Stroke the
The Bulge Sign in ... #clinical #video ... #physicalexam #msk ... #orthopedics #sports ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... : SLE+++, Adult-onset ... Still disease, ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... signs and symptoms ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... Oral aphthae : SLE ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... phenomenon (16%) MSK ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... of the immune system ... ▪ Autoimmune diseases ... • Common Signs ... #Hematology #HemeOnc