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rheumatology treatment hemophagocytic lymphohistiocytosis syndrome acromegaly algorithm antinxp2 antinxp2dm behcet classification cryoglobulinemia dermatology dermatomyositis differential disease disorders endocrinology gastroenterology hemochromatosis
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
• Absence of skin ... min/1.73 m2 at diagnosis ... • Dialysis at diagnosis ... #Vasculitis #Management ... #Rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... involvement CML ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng/ml ... sIL-2R >2400 Ul/ml ... lymphoma, B-cell ... #management #treatment ... #summary #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis via genetic ... Low or absent NK cell ... Ferritin >500 ng/mL ... #management #treatment ... #hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
haploidentical>unrelated>HLA ... symptoms, unexplained hematologic ... extralymphatic tissues Diagnosis ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... (MCHL) - Lymphocyte ... lymph node biopsy (diagnostic ... classification #hematology ... #oncology #management
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
regarding the diagnosis ... Step 3: All patients ... including liver and hematologic ... SF of >1,000 μg/mL ... #management #hepatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... response to local skin ... test (this is a skin ... #management #signs ... #symptoms #rheumatology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
, hair growth, skin ... tags, skin thickening ... pancreatic islet cell ... levels to <1ng/mL ... adenoma, ↓(TFT, LH
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